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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">morpho</journal-id><journal-title-group><journal-title xml:lang="ru">Морфологические ведомости</journal-title><trans-title-group xml:lang="en"><trans-title>Morphological newsletter</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1812-3171</issn><issn pub-type="epub">2686-8741</issn><publisher><publisher-name>Private Medical University REAVIZ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/mv-mn.18(26).01.24-27</article-id><article-id custom-type="elpub" pub-id-type="custom">morpho-101</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH ARTICLES</subject></subj-group></article-categories><title-group><article-title>МОРФОЛОГИЧЕСКИЕ ИЗМЕНЕНИЯ В ПОЧКЕ У ПАЦИЕНТОВ С ГНОЙНЫМ ПИЕЛОНЕФРИТОМ</article-title><trans-title-group xml:lang="en"><trans-title>KIDNEY MORPHOLOGICAL CHANGES IN THE PATIENTS WITH THE PURULENT PYELONEPHRITIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ананьев</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ananiev</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">urologkkb@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Антонов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Antonov</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">endour@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лубянский</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Lubyansky</surname><given-names>V. G.</given-names></name></name-alternatives><email xlink:type="simple">lvg51@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлев</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovlev</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">paradizo_7@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мотин</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Motin</surname><given-names>Yu. G.</given-names></name></name-alternatives><email xlink:type="simple">ygmotin@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Алтайская краевая клиническая больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Altai Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлов; Городская больница Святого Великомученика Георгия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov First Saint-Petersburg State Medical University; City Hospital of Saint Great Martyr George</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Алтайский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Altai State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2018</year></pub-date><volume>26</volume><issue>1</issue><fpage>24</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ананьев В.А., Антонов А.В., Лубянский В.Г., Яковлев В.А., Мотин Ю.Г., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Ананьев В.А., Антонов А.В., Лубянский В.Г., Яковлев В.А., Мотин Ю.Г.</copyright-holder><copyright-holder xml:lang="en">Ananiev V.A., Antonov A.V., Lubyansky V.G., Yakovlev V.A., Motin Y.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.morpholetter.com/jour/article/view/101">https://www.morpholetter.com/jour/article/view/101</self-uri><abstract><p>В статье представлены современные статистические данные по распространенности гнойного пиелонефрита в России, показан патогенез развития гнойного пиелонефрита с точки зрения нарушения кровообращения в почке на примере 23 пациентов, прооперированных в условиях урологического отделения Алтайской Краевой клинической больницы по оригинальному методу в период с 2016 г. по 2017 г. Морфологические исследования проводились в отделении патологической анатомии. Дана оценка морфологическим нарушениям в почке со значительными изменениями в микроциркуляторном русле в период проведения операции из зоны апостем, из зоны перифокального воспаления на расстоянии 1 см от очагов деструкции и из условно здоровых участков почечной паренхимы этой же почки электронно-микроскопическим методом. Дополнительно исследовали участки тканей почек, удаленных вследствие наступивших в них необратимых деструктивных изменений. Установлено , что необратимое развитие острого гнойного пиелонефрита связано с ишемией почечной ткани и для достижения хороших результатов в лечения пациентов должны быть проведены мероприятия по восстановлению утраченного артериального кровотока.</p></abstract><trans-abstract xml:lang="en"><p>The article presents modern statistical data on the prevalence of purulent pyelonephritis in Russia, shows the pathogenesis of purulent pyelonephritis development from the point of view of circulatory disorders in the kidney on the example of 23 patients operated under the conditions of the urology department of the Altai Regional Clinical Hospital by the original method in the period from 2016 to 2017 Morphological studies were carried out in the department of pathological anatomy. The evaluation of morphological disorders in the kidney with significant changes in the microcirculatory bed during the operation from the apostemic zone, from the perifocal inflammation zone at a distance of 1 cm from the lesion sites and from the conventionally healthy areas of the parenchyma of the same kidney by electron microscopy. Additionally, the sections of the kidney tissues that were removed due to the irreversible destructive changes that occurred in them were examined. It was established that the irreversible development of acute purulent pyelonephritis is associated with ischemia of the renal tissue and to achieve good results in the treatment of patients, measures should be taken to restore the lost arterial blood flow.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>морфология почки</kwd><kwd>гнойный пиелонефрит</kwd><kwd>микроциркуляторное русло</kwd><kwd>апостема</kwd></kwd-group><kwd-group xml:lang="en"><kwd>kidney morphology</kwd><kwd>purulent pyelonephritis</kwd><kwd>microcirculatory bed</kwd><kwd>apostem</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Polyantsev A.A., Sidorov D.N., Derevyanko I.V. Kuznetsov A.A. Results of diagnosis and treatment of acute pyelonephritis (retrospective study). VolGMU: Department of general surgery with the course of Urology, 2016. 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