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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">morpho</journal-id><journal-title-group><journal-title xml:lang="ru">Морфологические ведомости</journal-title><trans-title-group xml:lang="en"><trans-title>Morphological newsletter</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1812-3171</issn><issn pub-type="epub">2686-8741</issn><publisher><publisher-name>Private Medical University REAVIZ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/mv-mn.2018.26(3):18-22</article-id><article-id custom-type="elpub" pub-id-type="custom">morpho-132</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH ARTICLES</subject></subj-group></article-categories><title-group><article-title>ДЕСТРУКТИВНО-НЕКРОТИЧЕСКИЕ ПРОЦЕССЫ КОСТНО-ХРЯЩЕВОГО КОМПЛЕКСА ГРУДИНЫ ПРИ ИНФЕКЦИОННО-ВОСПАЛИТЕЛЬНЫХ ОСЛОЖНЕНИЯХ ПОСЛЕ ХИРУРГИЧЕСКИХ ОПЕРАЦИЙ НА ОТКРЫТОМ СЕРДЦЕ</article-title><trans-title-group xml:lang="en"><trans-title>DESTRUCTIVE NECROTIC PROCESSES OF THE STERNUM'S BONE-CARTILAGINOUS COMPLEX AT INFECTIOUS AND INFLAMMATORY COMPLICATIONS AFTER SURGICAL OPERATIONS ON OPEN HEART</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Касатов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasatov</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">a.kasatov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Четвертных</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chetvertnykh</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">nauka@psma.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щеткина</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shchetkina</surname><given-names>I. N.</given-names></name></name-alternatives><email xlink:type="simple">irina.schetkina@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трефилова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Trefilova</surname><given-names>Y. V.</given-names></name></name-alternatives><email xlink:type="simple">yutrefilova@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Пермская краевая клиническая больница; Пермский государственный медицинский университет имени академика Е.А. Вагнера</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Пермский государственный медицинский университет имени академика Е.А. Вагнера</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>Пермская краевая клиническая больница</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2018</year></pub-date><volume>26</volume><issue>3</issue><fpage>18</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Касатов А.В., Четвертных В.А., Щеткина И.Н., Трефилова Ю.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Касатов А.В., Четвертных В.А., Щеткина И.Н., Трефилова Ю.В.</copyright-holder><copyright-holder xml:lang="en">Kasatov A.V., Chetvertnykh V.A., Shchetkina I.N., Trefilova Y.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.morpholetter.com/jour/article/view/132">https://www.morpholetter.com/jour/article/view/132</self-uri><abstract><p>Изучены особенности и степень выраженности декструктивно-некротических процессов костно-хрящевого комплекса грудины при различных клинических формах инфекционно-воспалительных осложнений, возникших после операций на открытом сердце. Установлено, что у пациентов с диагнозом нестабильность грудины патоморфологические изменения костной ткани грудины развиваются в области продольного разреза. Они характеризуются поражением костного мозга, нарушением кровоснабжения, формированием очагов нагноения и некроза костной ткани. У пациентов с диагнозами «остеомиелит и стерномедиастинит» деструктивно-некротические процессы распространяются на различные участки костно- хрящевого аппарата грудины, сопровождаются развитием очагов полной деструкции кости, образованием секвестров и свищевых ходов. В ряде случаев гнойный процесс распространяется на плевру и средостение. Этиопатогенами наиболее выраженных патоморфологических процессов являлись Staphylococcus aureus и Pseudomonas aeruginosa.</p></abstract><trans-abstract xml:lang="en"><p>The features and severity of destructive-necrotic processes of the bone-cartilage complex of the sternum in various clinical forms of infectious and inflammatory complications arising after open-heart surgery have been studied. It has been established that in patients with a diagnosis of instability of the sternum, pathological changes in the bone tissue of the sternum develop in the area of the longitudinal incision. They are characterized by lesions of the bone marrow, impaired blood supply, the formation of foci of suppuration and necrosis of bone tissue. In patients with diagnoses of “osteomyelitis and sternomediastinitis,” destructive-necrotic processes spread to various parts of the bone and cartilage apparatus of the sternum, accompanied by the development of centers of complete bone destruction, the formation of sequestrum and fistulous passages. In some cases, the purulent process extends to the pleura and mediastinum. The etiopathogens of the most pronounced pathological processes were Staphylococcus aureus and Pseudomonas aeruginosa.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>деструктивно-некротические процессы</kwd><kwd>патологическая морфология</kwd><kwd>кардиохирургия</kwd><kwd>открытое сердце</kwd></kwd-group><kwd-group xml:lang="en"><kwd>destructive and necrotic processes</kwd><kwd>pathological morphology</kwd><kwd>cardiac surgery</kwd><kwd>open heart</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bokeriia L.A., Beloborodova N.V. Infektsiia v kardiokhirurgii.- M.: Izd-vo NTSSSKH im. A.N. Bakuleva RAMN, 2007.- 582s.</mixed-citation><mixed-citation xml:lang="en">Bokeriia L.A., Beloborodova N.V. Infektsiia v kardiokhirurgii.- M.: Izd-vo NTSSSKH im. A.N. 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