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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">morpho</journal-id><journal-title-group><journal-title xml:lang="ru">Морфологические ведомости</journal-title><trans-title-group xml:lang="en"><trans-title>Morphological newsletter</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1812-3171</issn><issn pub-type="epub">2686-8741</issn><publisher><publisher-name>Private Medical University REAVIZ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/mv-mn.2019(27).3.24-31</article-id><article-id custom-type="elpub" pub-id-type="custom">morpho-391</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH ARTICLES</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ ГИДРАВЛИЧЕСКОГО ЭФФЕКТА ГЕМОДИНАМИКИ ПРИ ЭКСТРАСИСТОЛИИ НА МОРФОЛОГИЮ МАГИСТРАЛЬНЫХ АРТЕРИЙ</article-title><trans-title-group xml:lang="en"><trans-title>THE INFLUENCE OF THE HYDRAULIC EFFECT OF THE BLOOD DYNAMICS AT THE EXTRASYSTOLY ON THE MORPHOLOGY OF MAINSTREAM ARTERIES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Германова</surname><given-names>Ольга Андреевна</given-names></name><name name-style="western" xml:lang="en"><surname>Germanova</surname><given-names>O. A.</given-names></name></name-alternatives><email xlink:type="simple">olga_germ@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Германов</surname><given-names>Владимир Андреевич</given-names></name><name name-style="western" xml:lang="en"><surname>Germanov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">olga_germ@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанов</surname><given-names>Михаил Юрьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanov</surname><given-names>M. Y.</given-names></name></name-alternatives><email xlink:type="simple">olga_germ@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Германов</surname><given-names>Андрей Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Germanov</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">olga_germ@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прохоренко</surname><given-names>Инга Олеговна</given-names></name><name name-style="western" xml:lang="en"><surname>Prokhorenko</surname><given-names>I. O.</given-names></name></name-alternatives><email xlink:type="simple">ingaproch@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пискунов</surname><given-names>Максим Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Piskunov</surname><given-names>M. V.</given-names></name></name-alternatives><email xlink:type="simple">olga_germ@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Самарский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Медицинский университет РЕАВИЗ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical University REAVIZ</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2019</year></pub-date><volume>27</volume><issue>3</issue><fpage>24</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Германова О.А., Германов В.А., Степанов М.Ю., Германов А.В., Прохоренко И.О., Пискунов М.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Германова О.А., Германов В.А., Степанов М.Ю., Германов А.В., Прохоренко И.О., Пискунов М.В.</copyright-holder><copyright-holder xml:lang="en">Germanova O.A., Germanov V.A., Stepanov M.Y., Germanov A.V., Prokhorenko I.O., Piskunov M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.morpholetter.com/jour/article/view/391">https://www.morpholetter.com/jour/article/view/391</self-uri><abstract><p>Влияние различных видов экстрасистолии на изменение артериальной гемодинамики и морфологию изменений стенки магистральных артериальных сосудов не достаточно изучено. Цель исследования - определить эффекты гидравлического удара на гемодинамику магистральных артерий при различных видах нарушений ритма сердца. Исследование проведено на 228 пациентах (122 мужчин и 106 женщин) в возрасте от 43 до 76 лет, средний возраст составил 62±4,3 лет. Для анализа использованы сопоставлены данные апекс-кардиографии, суточного мониторирования по Холтеру, эхокардиографии, электрокардиографии, сфигмографии, цветового допплеровского картирования сосудов головы и шеи и конечностей. Гидравлический удар при экстрасистолах приводит к механическому повреждению эндотелия артериальной стенки и служит пусковым механизмом воспаления и активация процесса неолипогенеза, формированию атером. Дополнительные гидравлические волны способствуют травматизации сосудистой стенки, росту и увеличению площади атером. Описанные морфологические изменения сосудистой стенки авторы описывают как «синдром гидравлического удара» и анализируют его роль и патофизиологические механизмы развития сосудистых осложнений при экстрасистолиях и реконструктивных операциях на артериальных сосудах.</p></abstract><trans-abstract xml:lang="en"><p>The influence of various types of extrasystole on the change in arterial hemodynamics and the morphology of changes in the wall of the mainstream arterial vessels is not well understood. The purpose of the study was to determine the effects of water hammer on the hemodynamics of the main arteries in various types of extrasystoly. The study was conducted on 228 patients (122 men and 106 women) aged 43 to 76 years, the average age was 62 ± 4.3 years. For the analysis, the data apex-cardiography, daily monitoring by Holter, echocardiography, electrocardiography, sphygmography, color Doppler mapping of the vessels of the head and neck and extremities were compared. Water hammer of extrasystoles leads to mechanical damage to the endothelium of the arterial wall and serves as a trigger for inflammation and activation of the process of neolipogenesis, the formation of the atheroma. Additional hydraulic waves contribute to trauma to the vascular wall, growth and increase in area of atheromas. The described morphological changes in the vascular wall, the authors describe as «water hammer syndrome» and analyze its role and pathophysiological mechanisms of the development of vascular complications at extrasystoles and reconstructive operations on arterial vessels.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артерии</kwd><kwd>морфология сосудистой стенки</kwd><kwd>экстрасистолия</kwd><kwd>гемодинамика</kwd><kwd>arteries</kwd><kwd>morphology of blood vessel's wall</kwd><kwd>extrasystoly</kwd><kwd>blood dynamics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
