<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">morpho</journal-id><journal-title-group><journal-title xml:lang="ru">Морфологические ведомости</journal-title><trans-title-group xml:lang="en"><trans-title>Morphological newsletter</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1812-3171</issn><issn pub-type="epub">2686-8741</issn><publisher><publisher-name>Private Medical University REAVIZ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/mv-mn.2022.30(3).589</article-id><article-id custom-type="elpub" pub-id-type="custom">morpho-589</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH ARTICLES</subject></subj-group></article-categories><title-group><article-title>АНАТОМИЧЕСКОЕ ОБОСНОВАНИЕ ИЗОЛИРОВАННОЙ ДОЛЕВОЙ ПОРТО-КАВАЛЬНОЙ ПЕРФУЗИИ ПЕЧЕНИ</article-title><trans-title-group xml:lang="en"><trans-title>THE ANATOMICAL GROUNDING OF ISOLATED LOBAR PORTOCAVAL PERFUSION OF THE LIVER</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3240-0303</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тягун</surname><given-names>Валерий Сергеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Tyagun</surname><given-names>Valery S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>старший ординатор хирургического отделения</p></bio><bio xml:lang="en"><p>Senior Ordinator of the Surgical Department of the Military Hospital</p></bio><email xlink:type="simple">dr.tyagun@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6836-5650</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гайворонский</surname><given-names>Иван Васильевич</given-names></name><name name-style="western" xml:lang="en"><surname>Gaivoronsky</surname><given-names>Ivan V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, заведующий кафедрой нормальной анатомии</p></bio><bio xml:lang="en"><p>Doctor of Medical Sciences, Professor, Head of the Department of Normal Anatomy</p></bio><email xlink:type="simple">i.v.gaivoronsky@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4519-0018</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суров</surname><given-names>Дмитрий Александрович</given-names></name><name name-style="western" xml:lang="en"><surname>Surov</surname><given-names>Dmitry A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, доцент, заместитель начальника кафедры военно-морской хирургии</p></bio><bio xml:lang="en"><p>Doctor of Medical Sciences, Docent, Deputy Head of the Department of Naval Surgery</p></bio><email xlink:type="simple">sda120675@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1120-6285</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыбаков</surname><given-names>Александр Сергеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Rybakov</surname><given-names>Aleksandr S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>начальник медицинской службы</p></bio><bio xml:lang="en"><p>Head of Medical Service</p></bio><email xlink:type="simple">pushchin2022@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7658-0297</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильина</surname><given-names>Виктория Анатольевна</given-names></name><name name-style="western" xml:lang="en"><surname>Il'ina</surname><given-names>Viktoriya A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, руководитель патологоанатомического отделения</p></bio><bio xml:lang="en"><p>Doctor of Medical Sciences, Head of the Department of Pathology</p></bio><email xlink:type="simple">profkomniisp@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4499-066X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анохин</surname><given-names>Дмитрий Юрьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Anokhin</surname><given-names>Dmitry Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, начальник радиологического отделения клиники военно-полевой терапии кафедры военно-полевой терапии</p></bio><bio xml:lang="en"><p>Candidate of Medical Sciences, Head of the Branch of Radiology of the Clinic of Military Therapy of the Department of Military Therapy</p></bio><email xlink:type="simple">damixon@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Военный госпиталь, Волгоград</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Military Hospital, Volgograd</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Военно-медицинская академия имени С.М. Кирова, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kirov Military Medical Academy, Saint-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Военно-медицинская академия имени С.М.Кирова, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kirov Military Medical Academy, Saint-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Войсковая часть, Балтийск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Military Unit, Baltysk</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Санкт-Петербургский научно-исследовательский институт скорой помощи имени И.И. Джанелидзе, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Dzhanelidze Saint-Petersburg Research Institute of Emergency Care, Saint-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>12</day><month>03</month><year>2022</year></pub-date><volume>30</volume><issue>3</issue><fpage>37</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тягун В.С., Гайворонский И.В., Суров Д.А., Рыбаков А.С., Ильина В.А., Анохин Д.Ю., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Тягун В.С., Гайворонский И.В., Суров Д.А., Рыбаков А.С., Ильина В.А., Анохин Д.Ю.</copyright-holder><copyright-holder xml:lang="en">Tyagun V.S., Gaivoronsky I.V., Surov D.A., Rybakov A.S., Il'ina V.A., Anokhin D.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.morpholetter.com/jour/article/view/589">https://www.morpholetter.com/jour/article/view/589</self-uri><abstract><p>С развитием перфузионных технологий в онкологии проблема поиска оптимальных путей введения перфузатов приобрела принципиальный характер и в этой связи изучение особенностей ангиоархитектоники печени в норме и при патологии не теряет своей актуальности. Целью нашего исследования явилось изучение особенностей портальной архитектоники печени применительно к возможности ее изолированной долевой перфузии. Методами цветовой перфузии (n=50), раздельных инъекций отвердевающей массой и изготовлением коррозионных препаратов (n=3), микрофокусной ангиографии (n=8), транспаренхиматозных секций и световой микроскопии (n=5) исследовано 53 препарата печени, эксплантированных из не бальзамированных трупов людей, умерших от заболеваний, не связанных напрямую с исследуемым органом. В результате исследования установлено, что граница зон кровоснабжения долевыми ветвями воротной вены при введении красителей проходит по латеральной границе четвертого сегмента печени в проекции основного ствола средней печеночной вены, а не по серповидной связке. По критерию распределения ветвей воротной вены анатомическое и хирургическое понятия о междолевых границах печени не совпадают. Макро- и микроскопически видимые междолевые интраорганные портальные анастомозы в норме отсутствуют, что указывает на относительную обособленность долевого портального кровотока печени. Внутрипеченочное русло собственной печеночной артерии имеет богатую архитектонику в поверхностных слоях паренхимы и обильно кровоснабжает капсулу печени. При выполнении транспаренхиматозных секций границы зон кровоснабжения долевыми ветвями воротной вены совпадали с междолевыми границами во всех случаях наблюдениях. Также отмечалось соответствие топографии границы зон кровоснабжения долевыми ветвями воротной вены на диафрагмальной поверхности печени и в ее паренхиме. Таким образом представляется возможным достоверно определить указанную границу по изменению картины на поверхности препарата печени. Относительная автономность русел долевых ветвей воротной вены может быть использована для разработки методик сосудистой изоляции долевого портального кровотока печени для оценки ее селективной изолированной перфузии.</p></abstract><trans-abstract xml:lang="en"><p>With the development of perfusion technologies in oncology, the problem of finding the optimal ways to perfusates injections has become fundamental, and in this regard, the study of the features of liver angioarchitectonics in normal and pathological conditions does not lose its relevance. The aim of our study was to study the features of the portal architectonics of the liver in relation to the possibility of its isolated lobar perfusion. Using the methods of color perfusion (n=50), separate injections of a hardening mass and the preparation of corrosive preparations (n=3), microfocus angiography (n=8), transparenchymal sections and light microscopy (n=5), 53 liver preparations explanted from non-embalmed corpses of people who died from diseases not directly related to the liver pathology. As a result of the study, it was found that the border of the zones of blood supply by the lobar branches of the portal vein after the introduction of dyes passes along the lateral border of the fourth segment of the liver in the projection of the main trunk of the middle hepatic vein, and not along the falciform ligament. According to the distribution criterion of the portal vein branches, the anatomical and surgical concepts of the interlobar boundaries of the liver do not coincide. Macro- and microscopically visible interlobar intraorgan portal anastomoses are normally absent, which indicates the relative isolation of the lobar portal blood flow of the liver. The intrahepatic bed of the proper hepatic artery has a rich architectonics in the surface layers of the parenchyma and abundantly supplies the liver capsule with blood. When performing transparenchymal sections, the boundaries of the blood supply zones of the lobar branches of the portal vein coincided with the interlobar boundaries in all cases of observation. It was also noted that the topography of the border of the blood supply zones with the lobar branches of the portal vein to match the diaphragmatic surface of the liver and in its parenchyma. Thus, it seems possible to reliably determine the indicated boundary by the pattern on the surface of the liver preparation. The relative autonomy of the channels of the lobar portal vein branches can be used to develop techniques for vascular isolation of the lobar portal blood flow in the liver to assess its selective isolated perfusion.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>анатомия печени</kwd><kwd>воротная вена печени</kwd><kwd>портальные анастомозы</kwd><kwd>сегменты печени</kwd><kwd>методы перфузии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver anatomy</kwd><kwd>liver portal vein</kwd><kwd>portal anastomoses</kwd><kwd>liver segments</kwd><kwd>perfusion methods</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Правительство Санкт-Петербурга</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Abdulaev MA, Napol'skaya EV, Tsikoridze MYu. Sovremennoe sostoyanie problemy maloinvazivnykh metodov lokal'nogo lecheniya metastazov kolorektal'nogo raka v pecheni (obzor literatury). Tazovaya khirurgiya i onkologiya. 2016;6(1):43-47. In Russian</mixed-citation><mixed-citation xml:lang="en">Abdulaev MA, Napol'skaya EV, Tsikoridze MYu. Sovremennoe sostoyanie problemy maloinvazivnykh metodov lokal'nogo lecheniya metastazov kolorektal'nogo raka v pecheni (obzor literatury). Tazovaya khirurgiya i onkologiya. 2016;6(1):43-47. In Russian</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Nasyrov AR, Pirtskhalava TL, Korovina YaV. Khimioterapiya patsientov s nerezektabel'nymi kolorektal'nymi metastazami v pechen': sistemnaya ili regionarnaya? Voprosy onkologii. 2011;57(2):192–198. In Russian</mixed-citation><mixed-citation xml:lang="en">Nasyrov AR, Pirtskhalava TL, Korovina YaV. Khimioterapiya patsientov s nerezektabel'nymi kolorektal'nymi metastazami v pechen': sistemnaya ili regionarnaya? Voprosy onkologii. 2011;57(2):192–198. In Russian</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Murzaliev EM, Mamashev NDzh, Bebezov BKh. Khirurgicheskoe lechenie metastazov kolorektal'nogo raka v pechen'. Vestnik Vestnik Kyrgyzsko-Rossyskogo Slavyanskogo Universiteta. 2015;2(2):97-101. In Russian</mixed-citation><mixed-citation xml:lang="en">Murzaliev EM, Mamashev NDzh, Bebezov BKh. Khirurgicheskoe lechenie metastazov kolorektal'nogo raka v pechen'. Vestnik Vestnik Kyrgyzsko-Rossyskogo Slavyanskogo Universiteta. 2015;2(2):97-101. In Russian</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Aigner K, Walther H, Tonn J, et al. First experimental and clinical results of isolated liver perfusion with cytotoxics in metastases from colorectal primary. Recent Results Cancer Research. 1983;86:99–102. DOI: 10.1007/978-3-642-82025-0_18</mixed-citation><mixed-citation xml:lang="en">Aigner K, Walther H, Tonn J, et al. First experimental and clinical results of isolated liver perfusion with cytotoxics in metastases from colorectal primary. Recent Results Cancer Research. 1983;86:99–102. DOI: 10.1007/978-3-642-82025-0_18</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Solt DB, Hay JB, Farber E. Comparison of the blood supply to diethylnitrosamine-induced hyperplastic nodules and hepatomas and to the surrounding liver. Cancer research. 1977;37(6):1686-1691</mixed-citation><mixed-citation xml:lang="en">Solt DB, Hay JB, Farber E. Comparison of the blood supply to diethylnitrosamine-induced hyperplastic nodules and hepatomas and to the surrounding liver. Cancer research. 1977;37(6):1686-1691</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Voboril R. Blood supply of metastatic liver tumors: an experimental study. International surgery. 2005;90(2):71-77</mixed-citation><mixed-citation xml:lang="en">Voboril R. Blood supply of metastatic liver tumors: an experimental study. International surgery. 2005;90(2):71-77</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Cherkasov MF, Grоshilin VS, Pomazkov AA, Dmitriev AV. Surgical and combined treatment of liver metastases in colorectal cancer. Fundamental Research. 2015; (1): 1491-1499.</mixed-citation><mixed-citation xml:lang="en">Cherkasov MF, Grоshilin VS, Pomazkov AA, Dmitriev AV. Surgical and combined treatment of liver metastases in colorectal cancer. Fundamental Research. 2015; (1): 1491-1499.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Breedis C, Young G. The blood supply of neoplasms in the liver. American Journal of Pathology. 1954;30(5):969</mixed-citation><mixed-citation xml:lang="en">Breedis C, Young G. The blood supply of neoplasms in the liver. American Journal of Pathology. 1954;30(5):969</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Favelier S, Germain T, Genson P-Y, et al. Anatomy of liver arteries for interventional radiology. Diagnostic and interventional imaging. 2015;96(6):537-546. DOI:10.1016/j.diii.2013.12.001</mixed-citation><mixed-citation xml:lang="en">Favelier S, Germain T, Genson P-Y, et al. Anatomy of liver arteries for interventional radiology. Diagnostic and interventional imaging. 2015;96(6):537-546. DOI:10.1016/j.diii.2013.12.001</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Matsui O, Kadoya M, Kameyama T, et al. Benign and malignant nodules in cirrhotic livers: distinction based on blood supply. Radiology. 1991;178(2):493-497. DOI: 10.1148/radiology.178.2.1846240</mixed-citation><mixed-citation xml:lang="en">Matsui O, Kadoya M, Kameyama T, et al. Benign and malignant nodules in cirrhotic livers: distinction based on blood supply. Radiology. 1991;178(2):493-497. DOI: 10.1148/radiology.178.2.1846240</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rogers W, Edlich RF, Aust JB. Tumor blood flow: II. Distribution of blood flow in experimental tumors. Angiology. 1969;20(7):374-387. DOI:10.1177/000331976902000702</mixed-citation><mixed-citation xml:lang="en">Rogers W, Edlich RF, Aust JB. Tumor blood flow: II. Distribution of blood flow in experimental tumors. Angiology. 1969;20(7):374-387. DOI:10.1177/000331976902000702</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Stribley KV, Gray BN, Chmiel RL, et al. Internal radiotherapy for hepatic metastases II: The blood supply to hepatic metastases. Journal of Surgical Research. 1983;34(1):25-32. DOI:10.1016/0022-4804(83)90018-5</mixed-citation><mixed-citation xml:lang="en">Stribley KV, Gray BN, Chmiel RL, et al. Internal radiotherapy for hepatic metastases II: The blood supply to hepatic metastases. Journal of Surgical Research. 1983;34(1):25-32. DOI:10.1016/0022-4804(83)90018-5</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Mitina LA, Stepanov SO, Sidorov DV i dr. Uzi pecheni s kontrastom pri metastazakh kolorektal’nogo raka v pechen’. Koloproktologiya. 2017;2(60)suppl.:32-36. In Russian.</mixed-citation><mixed-citation xml:lang="en">Mitina LA, Stepanov SO, Sidorov DV i dr. Uzi pecheni s kontrastom pri metastazakh kolorektal’nogo raka v pechen’. Koloproktologiya. 2017;2(60)suppl.:32-36. In Russian.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Bengmark S, Rosengren K. Angiographic study of the collateral circulation to the liver after ligation of the hepatic artery in man. The American Journal of Surgery. 1970;119(6):620-624</mixed-citation><mixed-citation xml:lang="en">Bengmark S, Rosengren K. Angiographic study of the collateral circulation to the liver after ligation of the hepatic artery in man. The American Journal of Surgery. 1970;119(6):620-624</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Guadagni S, Pizzutilli A, Mancini E, et al. Significance of duplex/colour Doppler sonography in hepatic arterial chemotherapy for patients with liver metastases from colorectal carcinoma. European Journal of Surgical Oncology (EJSO). 2000;26(4):381-386. DOI: 10.1053/ejso.1999.0903</mixed-citation><mixed-citation xml:lang="en">Guadagni S, Pizzutilli A, Mancini E, et al. Significance of duplex/colour Doppler sonography in hepatic arterial chemotherapy for patients with liver metastases from colorectal carcinoma. European Journal of Surgical Oncology (EJSO). 2000;26(4):381-386. DOI: 10.1053/ejso.1999.0903</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Zogot SR, Akberov RF. Chastota, luchevaya semiotika metastazov v pechen' opukholey razlichnoy lokalizatsii po rezul'tatam kompleksnogo luchevogo issledovaniya. Prakticheskaya meditsina. 2013;2(67):119-122. In Russian</mixed-citation><mixed-citation xml:lang="en">Zogot SR, Akberov RF. Chastota, luchevaya semiotika metastazov v pechen' opukholey razlichnoy lokalizatsii po rezul'tatam kompleksnogo luchevogo issledovaniya. Prakticheskaya meditsina. 2013;2(67):119-122. In Russian</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kan Z. Dynamic study of iodized oil in the liver and blood supply to hepatic tumors. An experimental investigation in several animal species. Acta Radiologica. Supplement. 1996;408:1-25.</mixed-citation><mixed-citation xml:lang="en">Kan Z. Dynamic study of iodized oil in the liver and blood supply to hepatic tumors. An experimental investigation in several animal species. Acta Radiologica. Supplement. 1996;408:1-25.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Taylor I, Bennett R, Sherriff S. The blood supply of colorectal liver metastases. British journal of cancer. 1978;38(6):749. DOI: 10.1038/bjc.1978.283</mixed-citation><mixed-citation xml:lang="en">Taylor I, Bennett R, Sherriff S. The blood supply of colorectal liver metastases. British journal of cancer. 1978;38(6):749. DOI: 10.1038/bjc.1978.283</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Nikfarjam M, Muralidharan V, Malcontenti-Wilson C, Christophi C. Scanning electron microscopy study of the blood supply of human colorectal liver metastases. European Journal of Surgical Oncology (EJSO). 2003;29(10):856-861. DOI: 10.1016/j.ejso.2003.08.009</mixed-citation><mixed-citation xml:lang="en">Nikfarjam M, Muralidharan V, Malcontenti-Wilson C, Christophi C. Scanning electron microscopy study of the blood supply of human colorectal liver metastases. European Journal of Surgical Oncology (EJSO). 2003;29(10):856-861. DOI: 10.1016/j.ejso.2003.08.009</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Surov DA, Solov'yov IA, Gaivoronsky IV i dr. Metod izolirovannoy dolevoy arterio-kaval'noy perfuzii pecheni v eksperimente. Patent RU 2726591. 16.11.2020. In Russian</mixed-citation><mixed-citation xml:lang="en">Surov DA, Solov'yov IA, Gaivoronsky IV i dr. Metod izolirovannoy dolevoy arterio-kaval'noy perfuzii pecheni v eksperimente. Patent RU 2726591. 16.11.2020. In Russian</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Lin G, Lunderquist A, Hagerstrand I, Boijsen E. Postmortem examination of the blood supply and vascular pattern of small liver metastases in man. Surgery. 1984;96(3):517-526</mixed-citation><mixed-citation xml:lang="en">Lin G, Lunderquist A, Hagerstrand I, Boijsen E. Postmortem examination of the blood supply and vascular pattern of small liver metastases in man. Surgery. 1984;96(3):517-526</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Lin G, Hagerstrand I, Lunderquist A. Portal blood supply of liver metastases. American journal of roentgenology. 1984;143(1):53-55. DOI: 10.2214/ajr.143.1.53</mixed-citation><mixed-citation xml:lang="en">Lin G, Hagerstrand I, Lunderquist A. Portal blood supply of liver metastases. American journal of roentgenology. 1984;143(1):53-55. DOI: 10.2214/ajr.143.1.53</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Ackerman NB, Lien WM, Kondi ES, Silverman NA. The blood supply of experimental liver metastases. I. The distribution of hepatic artery and portal vein blood to «smaIl» and «large» tumor. Surgery 1969;66:1067-1072</mixed-citation><mixed-citation xml:lang="en">Ackerman NB, Lien WM, Kondi ES, Silverman NA. The blood supply of experimental liver metastases. I. The distribution of hepatic artery and portal vein blood to «smaIl» and «large» tumor. Surgery 1969;66:1067-1072</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
