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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">morpho</journal-id><journal-title-group><journal-title xml:lang="ru">Морфологические ведомости</journal-title><trans-title-group xml:lang="en"><trans-title>Morphological newsletter</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1812-3171</issn><issn pub-type="epub">2686-8741</issn><publisher><publisher-name>Private Medical University REAVIZ</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">morpho-591</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH ARTICLES</subject></subj-group></article-categories><title-group><article-title>МОРФОМЕТРИЧЕСКАЯ АНАТОМИЯ ОБОЛОЧЕК ГЛАЗА В ПРОМЕЖУТОЧНОМ ПЛОДНОМ ПЕРИОДЕ ОНТОГЕНЕЗА ЧЕЛОВЕКА</article-title><trans-title-group xml:lang="en"><trans-title>THE MORPHOMETRIC ANATOMY OF THE EYE SHELLS IN THE INTERMEDIATE FETAL PERIOD OF HUMAN ONTOGENESIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Найденова</surname><given-names>Светлана Игоревна</given-names></name><name name-style="western" xml:lang="en"><surname>Naydenova</surname><given-names>Svetlana I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры анатомии человека</p></bio><bio xml:lang="en"><p>Assistant of the Human Anatomy Department</p></bio><email xlink:type="simple">svetaogma@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Луцай</surname><given-names>Елена Дмитриевна</given-names></name><name name-style="western" xml:lang="en"><surname>Lutsay</surname><given-names>Elena D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, доцент, профессор кафедры анатомии человека</p></bio><bio xml:lang="en"><p>Doctor of Medical Sciences, Docent, Professor of the Human Anatomy Department</p></bio><email xlink:type="simple">k_anatomy@orgma.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Астафьев</surname><given-names>Игорь Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Astaf'ev</surname><given-names>Igor V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, доцент кафедры офтальмологии</p></bio><bio xml:lang="en"><p>Candidate of Medical Sciences, Assistant Professor of the Department of Ophthalmology</p></bio><email xlink:type="simple">k_ophtalm@orgma.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Оренбургский государственный медицинский университет, Оренбург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Orenburg State Medical University, Orenburg</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>06</month><year>2021</year></pub-date><volume>29</volume><issue>2</issue><fpage>51</fpage><lpage>57</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Найденова С.И., Луцай Е.Д., Астафьев И.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Найденова С.И., Луцай Е.Д., Астафьев И.В.</copyright-holder><copyright-holder xml:lang="en">Naydenova S.I., Lutsay E.D., Astaf'ev I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.morpholetter.com/jour/article/view/591">https://www.morpholetter.com/jour/article/view/591</self-uri><abstract><p>Исследование процессов морфогенеза глаза в плодном периоде онтогенеза является актуальным с точки зрения понимания механизмов формирования физиологической гиперметропии новорожденных детей и миопии в детском возрасте в последующем. Наибольшим преобразованиям у плода человека подвержены изменениям роговица и оболочки глазного яблока в области экватора и в области диска зрительного нерва. Наиболее активно в целом глазное яблоко растет и развивается в промежуточном плодном периоде онтогенеза. Однако детали этого процесса недостаточно изучены. Цель исследования -  характеристика количественной макромикроскопической анатомии оболочек глазного яблока у плода человека в промежуточном плодном периоде онтогенеза.  Макроскопически и микроскопически методом гистотопографии изучена анатомия глазницы и глазного яблока плода в возрасте 14-27 недель. Были изучены три возрастные группы: I группа (14-18 недель) – 36% наблюдений, II группа (19-23 недели) – 38% наблюдений, III группа (24-27 недель) – 26% наблюдений, из них 50% наблюдений мужского пола и 50% женского пола. Гистотопограммы позволили охарактеризовать морфологию всех оболочек глазного яблока (фиброзной, сосудистой оболочки и сетчатки), а также проследить их ход во всех его участках. Представлено описание срединно-горизонтальных и срединно-сагиттальных гистотопограмм, окрашенных по Ван-Гизон и дана количественная характеристика толщины всех оболочек глазного яблока в области экватора, заднего полюса глаза и роговицы, установлены половые различия и указаны темпы их роста. В промежуточном плодном периоде онтогенеза человека происходит изменение переднее-заднего размера глазного яблока от 6,91±1,22 мм до 12,25±1,61 мм. На отдельных этапах всего промежуточного плодного периода онтогенеза человека соотношение толщины оболочек глаза является сопоставимым (толщина склеры – 51%, сосудистой оболочки – 29%, сетчатки – 20%). Изучение темпов роста толщины оболочек глазного яблока выявило наибольший ее прирост в исследованном периоде онтогенеза в области заднего полюса (69,06%).</p></abstract><trans-abstract xml:lang="en"><p>The study of the processes of eye morphogenesis in the fetal period of ontogenesis is relevant from the point of view of understanding the mechanisms of the formation of physiological hyperopia in newborns and myopia in childhood later. The greatest transformations in the human fetus are subject to changes in the cornea and shells of the eyeball in the equator area and in the optic nerve disk area. In general, the eyeball grows and develops most actively in the intermediate fetal period of ontogenesis. However, the details of this process are not well understood. The aim of the study is to characterize the quantitative macro-microscopic anatomy of the shells of the eyeball in a human fetus in the intermediate fetal period of ontogenesis. Macroscopically and microscopically, the anatomy of the orbit and eyeball of the fetus at the age of 14-27 weeks was studied by histo-topography. Three age groups were studied: Group I (14-18 weeks) - 36% of observations, Group II (19-23 weeks) - 38% of observations, Group III (24-27 weeks) - 26% of observations, of which 50% of observations male and 50% female. Histo-topograms made it possible to characterize the morphology of all shells of the eyeball (fibrous, choroid and retina), as well as to trace their course in all its parts. The description of the mid-horizontal and mid-sagittal histo-tomograms, stained according to Van Gieson, is presented and a quantitative characteristic of the thickness of all shells of the eyeball in the equator, the posterior pole of the eye and the cornea is given, sex differences are established and their growth rates are indicated. In the intermediate fetal period of human ontogenesis, the anterior-posterior size of the eyeball changes from 6.91±1.22 mm to 12.25±1.61 mm. At some stages of the entire intermediate fetal period of human ontogenesis, the ratio of the thickness of the shells of the eye is comparable (thickness of the sclera - 51%, of the choroid - 29%, of the retina - 20%). The study of the growth rate of the thickness of the shells of the eyeball revealed its greatest increase in the studied period of ontogenesis in the region of the posterior pole (69.06%).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>оболочки глаза</kwd><kwd>развитие глаза человека</kwd><kwd>плод человека</kwd><kwd>промежуточный плодный период</kwd></kwd-group><kwd-group xml:lang="en"><kwd>eye shells</kwd><kwd>human eye development</kwd><kwd>human fetus</kwd><kwd>intermediate fetal period</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено при финансовой поддержке гранта Оренбургского государственного медицинского университета (приказ № 66 от 17.01.2020 г. Об утверждении программы «Университетский научный грант» на 2020 год)</funding-statement><funding-statement xml:lang="en">The research study was carried out with the fi-nancial support of a grant of the Orenburg State Medical University (Order No. 66 of January 17, 2020, On the approval of the Program «University Scientific Grant»- 2020)</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Korovenkov RI. Nasledstvennye i vrozhdennye zabolevaniya glaza. SPb.: Ximizdat; 2006. 640s. Russian.</mixed-citation><mixed-citation xml:lang="en">Askarova ZF, Gorbatjuk TL, Bojchuk IM. Morfostrukturnye osobennosti zritel'nogo nerva i peripapilljarnyh volokon u detej s miopiej. Oftal'mologicheskij zhurnal. 2011;1(438):41-45.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Muxina AYu. 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