TO THE MEMORY OF PROFESSOR RAFAIL BOYKO - TO 90 YEARS ANNIVERSARY

The article is devoted to the biography of professor Rafail Boyko, Doctor of medical sciences, histologist, endocrinologist, Learner of Professor Boris Alyoshin, who made a significant contribution to the teaching of histology, embryology and cytology in soviet medical schools in the second half of the 20th century. He headed the Department of Histology and Embryology of the Izhevsk State Medical Institute (1972-1977), the Department of Histology and Embryology of the Kursk State Medical Institute (1977-1980), the Department of Physiology of the Kherson State University (1981-1995). Professor Rafail Boyko had a significant impact on the development of scientific morphological research and the formation of the scientific community in Russia and Ukraine. The purpose of the study is to restore the history of the formation of Russian science and the scientific morphological school of the outstanding Russian histologists Boris Lavrentiev - Boris Alyoshin, analysis of the scientific works of Professor Rafail Boyko, determination of his contribution to the development of the scientific community of morphologists and endocrinologists in Russia and Ukraine and to the system of higher medical education. The subject of the research in the article was the scientific biography of the scientist, histologist, physiologist and endocrinologist Rafail Boyko, one of the representatives of the famous scientific morphological school of histology. The object of the study was the scientific work of Rafail Boyko in 60th - 70th of 20th century. The research methods are based on comparative-historical, biographical, historical-scientific and documentary-retrospective research methods. The authors of the article prove the contribution of Professor Rafail Boyko in the development of the scientific community of morphologists and endocrinologists in Russia and Ukraine, in the structure and function of the hypothalamic-pituitary system and peripheral endocrine glands, in the development of histochemical and immunochemical research methods. He became one of the first researchers who stained and described the structure of adenohypophysis cells synthesizing adrenocorticotropic hormone. Authors show the contribution of Rafail Boyko in the development of the system of higher medical education in Russia and research centers in Ukraine and that the results of published scientific research by Professor Rafail Boyko are relevant at the present time.

1. Ivanov AV, Nikishina NA, Zatolokina MA, Puchkov VI. Istoricheskie aspekty izucheniya posledstviy gipotermii dlya funktsiy gipofiza i polovykh zhelez. Istoriya nauki i tekhniki. 2022;7:59-64. In Russian

2. Nikishina NA, Ivanov AV, Puchkov VI. Vklad kurskikh gistologov v razvitie endokrinologii v KhKh veke.- V kn.: Materialy mezhdunarodnoy nauchnoy i metodicheskoy konferentsii, posvyashchennoy godu fundamental'nykh nauk «Sovre-mennye aspekty morfologii, patomorfologii i onkopatologii organizma cheloveka».- Kursk, 2022.- S. 281-290. In Russian

3. Boyko RT. Izmenenie stimuliruyushchikh funktsiy gipofiza pri gipotermii na fone primeneniya narkoticheskikh veshchestv.- V kn.: Sb. nauch. tr. «Fiziologiya i patologiya endokrinnykh zhelez».- Khar'kov, 1961.- S. 15-17. In Russian

4. Boyko RT. Soderzhanie tireotropnogo i gonadotropnykh gormonov v gipofize samtsov i samok pri glubokoy gipoter-mii.- V kn.: Sb. nauch. tr. «Fiziologiya i patologiya endokrinnykh zhelez».- Khar'kov, 1962.- S. 58-61. In Russian

5. Boyko RT. Vliyanie gipoksii na funktsiyu nadpochechnikov u novorozhdennykh zhivotnykh.- V kn.: Fiziologiya i patolo-giya endokrinnoy sistemy. Khar'kov, 1965.- S. 69-70. In Russian

6. Boyko RT. Reaktsiya nevronov perednego gipotalamusa na gipoksiyu u zhivotnykh v period rannego ontogeneza.- V kn.: Voprosy klinicheskoy i teoreticheskoy meditsiny.- Kiev, 1969.- S. 145-146. In Russian

7. Boyko RT. Vliyanie gipoksii na endokrinnye zhelezy rastushchego organizma.- V kn.: Materialy VIII Vsesoyuznogo s"ezda anatomov, gistologov i embriologov.- Tashkent, 1974.- S. 254-255. In Russian

8. Boyko RT. Soderzhanie gomoripolozhitel'nogo neyrosekreta v gipotalamo-gipofizarnoy sisteme krys v postna-tal'nom ontogeneze.- V kn.: Materialy VII Mezhdunarodnogo simpoziuma po neyroendokrinologii. Leningrad, 1976.- S. 134-136. In Russian

9. Boyko RT. Osobennosti gistofiziologii sekretornogo protsessa kletok adenogipofiza pri reaktsii napryazheniya v zavisimosti ot vozrasta.- V kn.: Materialy II S"ezda endokrinologov USSR. Kiev, 1977.- S. 39-41. In Russian

10. Boyko RT, Ir'yanov YuM. Immunogistokhimicheskaya kharakteristika kletok adenogipofiza, produtsiruyushchikh adreno-kortikotropnyy gormon. Arkhiv anatomii, gistologii i embriologii. 1977;73(8):32-35. In Russian

11. Ir'yanov YuM, Ivshin BL, Boyko RT. Metodika dokrashivaniya preparatov pri immunofluorestsentnykh issledovani-yakh gipofiza. Arkhiv anatomii, gistologii i embriologii. 1978;75(7):96-98. In Russian

12. Boyko RT. Funktsional'naya aktivnost' kortikotropotsitov gipofiza pri razlichnom kharaktere smerti. Kazanskiy meditsinskiy zhurnal. 1978;5:193-196. In Russian

13. Boiko RT, Ir'yanov YuM. Immunochemical characterization of adenohypophyseal cells producing adrenocorticotrophic hor-mone. Neuroscience and Behavioral Physiology. 1979;9(3):316-319

14. Boyko RT. Lyuministsentnaya mikroskopiya v izuchenii nukleinovykh kislot endokrinnykh zhelez.- V kn.: Materialy I konferentsii po lyuministsentnomu analizu v biologii i meditsine. Riga, 1981.- S. 273-275. In Russian

15. Boyko RT. Sekretornaya aktivnost' adenogipofiza v usloviyakh blokady adrenergicheskikh vliyaniy gipotalamusa.- V kn.: Materialy Kh Vsesoyuznogo s"ezda anatomov, gistologov i embriologov.- Minsk, 1981.- S. 205-207. In Russian

16. Boyko RT. Sostoyanie tropnykh funktsiy adenogipofiza v usloviyakh pri khronicheskom stresse.- V kn.: Materialy I Vserossiyskogo s"ezda anatomov, gistologov i embriologov.- Orenburg, 1982.- S. 293-295. In Russian