MODERN METHODS OF THE PRODUCING OF CORROSIVE ANATOMICAL PREPARATIONS

One of the pressing modern problems of teaching morphology is to make the development and teaching of human anatomy as visual as possible. The organs demonstrated during the study of this discipline must retain their natural shape and size. The quality of the resulting preparations depends on the development of technologies for influencing biomaterial, its preservation and embalming. An accurate and visual preparation is the most important tool for demonstrating normal and pathologically altered organs and tissues. The purpose of this review is to analyze the literature data on modern methods for manufacturing corrosive anatomical preparations. The materials for the review were sources of anatomical literature devoted to the issues of anatomical technology, conservation and production of anatomical preparations for teaching students and museum affairs. The work highlights the history of the development of methods for manufacturing anatomical preparations for use in educational demonstration purposes. A detailed analysis of data on currently used methods for producing corrosive preparations was carried out. The advantages of corrosive preparations and polymerizing compositions in comparison with preparations made using wet fixation and plastination methods are shown. A comparative analysis of the characteristics of known polymerizing compositions is presented. The prospects for the development of the corrosion method and its use for the clarity of teaching in educational institutions of medical and biological profiles, as well as the study of three-dimensional configurations of organs and vessels when planning surgical interventions, are determined. The main promising directions for improving the corrosion method are the selection of polymerizing compositions that are rational in their properties, the development of technical devices to facilitate the filling of vascular beds with solutions, as well as other tubular and hollow organs and structures with a polymer solution. Taking into account the development of clinical anatomy and the growing interest in the individual characteristics of organs and their typical anatomy, this method can be used to visually study the variant anatomy and blood supply of complex parenchymal organs.

1. Nikolenko VN, Urakov A., Rastegaeva LB, i dr. Primenenie novogo konserviruyushсhego rastvora dlya khraneniya i demonstratsii anatomicheskikh preparatov. Morfologicheskie vedomosti. 2019;27(4):61-64. In Russian

2. Nikolenko VN, Dorosevich AE, Romanov NA, Nikityuk DB. Istoricheskiy aspekt anatomii: Rukovodstvo.– Smolensk: Rusich, 2015.– 544s. In Russian

3. Nikolenko VN, Oganesyan MV, Kudryashova VA, i dr. Chto mozhet priblizit' prepodavanie anatomii k potrebnostyam prakticheskoy meditsiny? Sovremennye problemy nauki i obrazovaniya. 2017(3):46. In Russian

4. Sirota ES, Gorduladze DN, Rapoport LM, i dr. Neinvazivnaya morfologicheskaya diagnostika lokalizovannykh obrazovaniy parenkhimy pochki (pilotnoe issledovanie). Russian Electronic Journal of Radiology. 2021;11(4):94-104. DOI:10.21569/2222-7415-2021-11-4-94-104. In Russian

5. Ovcharenko VV, Pikalyuk VS, Malov AE i dr. 3d-rekonstruktsiya, 3d-modelirovanie i 3d-pechat' kak forma vneauditornoy samostoyatel'noy uchebno-issledovatel'skoy raboty studentov (UIRS na kafedre normal'noy anatomii cheloveka meditsinskoy akademii imeni S.S. Georgievskogo. Krymskiy zhurnal eksperimental'noy i klinicheskoy meditsiny. 2016;6(3):240-245. In Russian

6. Hendriksen MMA. Casting life, casting death: connections between early modern anatomical corrosive preparations and artistic materials and techniques. Notes Rec R Soc Lond. 2019;73(3):369-397. DOI:10.1098/rsnr.2018.0068

7. Shkarubo MA, Dobrovol'sky GF, Polev GA, i dr. Sposob izgotovleniya anatomicheskikh preparatov golovnogo mozga cheloveka s in’’ektsiey sosudov tsetnym silikonom (tehnicheskoe opisanie). Voprosy neyrokhirurgii im. N.N. Burdenko. 2018;82(2):59-64. In Russian

8. Henry RW, von Hagens G, Seamans G. Cold temperature/Biodur® /S10/von Hagens'-Silicone plastination technique. Anat Histol Embryol 2019;48(6):532-538. DOI:10.1111/ahe.12472

9. Borzjak EI, Putalova IN, fon Hagens G. Anatomiya cheloveka. Fotografichesky atlas. Uchebnoe posobie. V 3-h tomakh. Tom 1.– GEOTAR-Media: M, 2014.– 480s. In Russian

10. Akopov AL, Ivanov VA. Ispol'zovanie biologicheskogo materiala i drugikh naglyadnykh posobiy dlya prepodavaniya normal'noy i klinicheskoy anatomii. Operativnaya khirurgiya i klinicheskaya anatomiya (Pirogovsky nauchny zhurnal). 2017;1(2):40-42. In Russian

11. Orlova LN, Shalygin SP. Modelirovanie korrozionnykh preparatov vnutrennikh organov zhivotnykh s primeneniem akrilovykh stomatologicheskikh plastmass. Fundamental'nye issledovaniya. 2013;4(3):650-654. In Russian

12. Suslov AV, Nikolenko VN, Chairkin IN, i dr. Ivan Sokolov and his post-mortem studies of the “hairy woman” Julia Pastrana and her son. Endeavour. 2021;45(3):100780. DOI: 10.1016/j.endeavour.2021.100780

13. Kagan II, Kim VI, Grekova NS, i dr. Sposob in’’ektsii limfaticheskoy sistemy. Patent na izobretenie RU 2207157 C2, 27.06.2003.- Zayavka № 2001125818/14 ot 20.09.2001. In Russian

14. Cornillie P, Casteleyn C, von Horst C, et al. Corrosion casting in anatomy: Visualizing the architecture of hollow structures and surface details. Anat Histol Embryol. 2019;48(6):591-604. DOI: 10.1111/ahe.12450. In Russian

15. Domagała Z, Domański J, Zimmer A, et al. Methodology of preparation of corrosive specimens from human placenta - A technical note. Ann Anat. 2020;228:151436. DOI:10.1016/j.aanat.2019.151436

16. Li J, Nie L, Li Z, et al. Maximizing modern distribution of complex anatomical spatial information: 3D reconstruction and rapid prototype production of anatomical corrosion casts of human specimens. Anat Sci Educ. 2012;5(6):330-339. DOI: 10.1002/ase.1287

17. Zolotukhin VO, Bessonova VV, Kozarezov SA, i dr. Izgotovlenie korrozionnykh preparatov na osnove bystro zatverdevayushchey plastmassy. Molodezhny innovatsionny vestnik. 2018;7(1):169-170. In Russian

18. Shaduro DV, Pikalyuk VS. Sposob izgotovleniya korrozionnykh anatomicheskikh preparatov. Patent na poleznuyu model' RU 153522 U1, 20.07.2015.- Zayavka № 2014154664/93 ot 29.12.2014. In Russian

19. Akilova AT. Metodika izgotovleniya korrozionnykh preparatov sosudov. Trudy Voenno-Morskoy Meditsinskoy Akademii. 1944;III(2):189–192. In Russian

20. Rueda-Esteban R, López-Mccormick J, Martínez D, et al. Corrosion casting, a known techniquefor the study and teaching of vascular and duct structure in anatomy. Int J Morphol. 2017;35(3):1147-1153

21. Kafarov ES, Dmitriev AV, Zenin OK, i dr. Novaya polimernaya rentgenkontrastnaya kompozitsiya dlya izgotovleniya korrozionnykh anatomicheskikh preparatov. Vestnik novykh medicinskikh tehnologiy. Elektronnoe izdanie. 2021;4:121–125. DOI:10.24412/2075-4094-2021-4-3-7. In Russian