The role of mineralization of environment in the development of thyroid pathology

Abstract

Objective: to study the relationship between the frequency of thyroid pathology of residents of the Penza city and the Penza region and the content of microelements in water and soil. Material and research methods: statistical data of thyroid disorders of residents of the Penza city and the Penza region and of the level of mineral contamination of environment from 2000 to 2013. Analyzed the content of iron, nitrites, fluorine in the water; cadmium, copper, lead and zinc in the soil. All cases of thyroid pathology were divided into 5 groups: diffuse goiter, multinodular goiter, hypothyroidism, hyperthyroidism, thyroiditis. Quantitative data were processed by variational-statistical methods, using the non-parametric correlation and dispersion factorial analysis. It has been established that there is a strong correlation between the content of zinc in the soil and the incidence of diffuse goiter, content of cadmium in the soil and the incidence of hypothyroidism and diffuse goiter, content of fluoride in water and incidence of thyrotoxicosis. Effect of mineralization is evident not only within the same year, but there is deferred effect.