KIDNEY MORPHOLOGICAL CHANGES IN THE PATIENTS WITH THE PURULENT PYELONEPHRITIS

Abstract

The article presents modern statistical data on the prevalence of purulent pyelonephritis in Russia, shows the pathogenesis of purulent pyelonephritis development from the point of view of circulatory disorders in the kidney on the example of 23 patients operated under the conditions of the urology department of the Altai Regional Clinical Hospital by the original method in the period from 2016 to 2017 Morphological studies were carried out in the department of pathological anatomy. The evaluation of morphological disorders in the kidney with significant changes in the microcirculatory bed during the operation from the apostemic zone, from the perifocal inflammation zone at a distance of 1 cm from the lesion sites and from the conventionally healthy areas of the parenchyma of the same kidney by electron microscopy. Additionally, the sections of the kidney tissues that were removed due to the irreversible destructive changes that occurred in them were examined. It was established that the irreversible development of acute purulent pyelonephritis is associated with ischemia of the renal tissue and to achieve good results in the treatment of patients, measures should be taken to restore the lost arterial blood flow.