MORPHOFUNCTIONAL CHARACTERISTICS OF TESTES IN WHITE RATS TREATED WITH BISPHENOL A AND TRICLOSAN
https://doi.org/10.20340/mv-mn.18(26).04.32-34
Abstract
We studied the effect of unstable ubiquitous endocrine disrupters bisphenol A (BPA) and triclosan (TCS) on the reproductive function of adult male Wistar rats. BPA and TCS concentrations were measured directly in testicular tissue by gas chromatography with mass spectrometry (GC-MS). Comparison groups were found to be statistically significantly different in the concentrations of bisphenol A and triclosan in testicular tissues. The study showed that bisphenol A and triclosan have a negative effect on the morphofunctional state of the male reproductive glands of sexually mature rats, causing a decrease in testicular mass, a decrease in parenchyma, the number and diameter of the seminiferous tubules, an increase in the number of convoluted seminiferous tubules with desquamated epithelium, and a decrease in sperm cells on the background of an increase in their atypical forms.
About the Authors
S. V. Chigrinets
South Ural State Medical University
Russian Federation
Russian Federation
G. V. Bryuhin
South Ural State Medical University
Russian Federation
Russian Federation
S. N. Zavyalov
South Ural State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Chigrinets S.V., Bryuhin G.V., Zavyalov S.N. MORPHOFUNCTIONAL CHARACTERISTICS OF TESTES IN WHITE RATS TREATED WITH BISPHENOL A AND TRICLOSAN. Morphological newsletter. 2018;26(4):32-34. (In Russ.) https://doi.org/10.20340/mv-mn.18(26).04.32-34
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