EXPRESSION OF CD68+, BCL-2+, KI-67+ IN SENTINEL, NATIVE AND POSTNATAL INDUCED LYMPH NODES
https://doi.org/10.20340/mv-mn.17(25).02.06
Abstract
Immunohistochemically features of postnatal induced lymph nodes in comparison with sentinel and native lymph nodes in the experiment were studied. For the postnatal formation of lymph nodes, an experiment was performed on 25 white male rats of the Wistar line. The first group of animals (15 rats) was treated with sarcoma M1, the second group consisted of intact animals (10 rats). In the experiment, the possibility of reproducing postnatal induction of neolymphogenesis in tumor growth was demonstrated in the model of sarcoma M1. The study demonstrated a high level of antigen stimulation of T and B lymphocytes in postnatal induced lymph nodes and showed the possible role of macrophage cells in stimulating neolymphogenesis and the formation of new lymph nodes.
Keywords
About the Authors
R. A. Rustamkhanov
Republic Clinical Cancer Center
Russian Federation
Russian Federation
O. V. Zayrat’Yants
Yevdokimov Moscow State University of Medicine and Dentistry
Russian Federation
Russian Federation
Sh. Kh. Gantsev
Bashkir State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Rustamkhanov R.A., Zayrat’Yants O.V., Gantsev Sh.Kh. EXPRESSION OF CD68+, BCL-2+, KI-67+ IN SENTINEL, NATIVE AND POSTNATAL INDUCED LYMPH NODES. Morphological newsletter. 2017;25(2):37-42. (In Russ.) https://doi.org/10.20340/mv-mn.17(25).02.06
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