MORPHOLOGICAL REACTION OF MAST CELLS IN REPARATIVE REGENERATION IN THE SKIN UNDER THE INFLUENCE OF REGIONAL FACTORS
https://doi.org/10.20340/mv-mn.2014.0(3):20-30
Abstract
Experimental study of the morphological response of mast cells with selective and combined influence of platelet-rich plasma on and aseptic suppurative course of the wound process in the skin. The experiment found that mast cells respond by changing the morphofunctional state on the inflammatory reaction in the area of the wound defect. The greatest intensity of this reaction is determined in aseptic wounds during selective action of platelet-rich plasma, as well as by the combined effect of pulse rehabilitation and platelet-rich plasma to treat the course of the wound process.
About the Authors
N. T. Alexeeva
ГБОУ ВПО «Воронежская государственная медицинская академия им. Н.Н. Бурденко» Минздрава России
Russian Federation
Russian Federation
D. S. Nikityuk
ГБОУ ВПО Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России
Russian Federation
Russian Federation
A. A. Glukhov
ГБОУ ВПО «Воронежская государственная медицинская академия им. Н.Н. Бурденко» Минздрава России
Russian Federation
Russian Federation
References
1. Пальцев М.А. Патологическая анатомия : в 3 кн./ М.А. Пальцев, Н.М. Аничков. - Москва : Медицина, 2001. - Кн. 1. - 527 с.
2. Патогенез и гистоморфологические особенности рубцовых изменений кожи / О.В. Жукова [и др.]//Клиническая дерматология и венерология, 2009. - Т. 3, № 4. С. 4-9.
3. Быков В.Л. Секреторные механизмы и секреторные продукты тучных клеток / В.Л. Быков // Морфология. - 1999. - Т. 115, № 2. - С. 64-72.
4. Маянский Д.Н. Лекции по клинической патологии : руководство для врачей /Д.Н. Маянский. -Москва : ГЭОТАР-Медиа, 2007. - 464 с.
5. Mast cell involvement in normal human skin wound healing: expression of monocyte chemoattractant protein-1 is correlated with recruitment of mast cell which synthesize interleukin-4 in vivo/A. Trautmann [etal.]//J. Pathol., 2000. - Vol. 190. - P. 100-106.
6. Nathan C. Oxygen and the inflammatory cell / C. Nathan//Nature, 2003. - Vol. 422. - P. 675-676.
7. Haynesworth S.E. Mitogenic stimulation of human mesenchymal stem cells by platelet release suggest a mechanism for enhancement of bone repair by platelet concentrates/S.E. Haynesworth [et al.]// Presented at the 48th Meeting of the Orthopedic Research Society, Boston, MA. - 2002.
8. Liu Y. Fibroblast proliferation due to exposure to a platelet concentrate in vitro is pH dependent/ Y. Liu [et al.] //Wound Repair Regen., 2002. - Vol. 10. - P. 336-340.
9. Sen C.K. Wound healing essentials: let there be oxygen/C.K. Sen// Wound Rep Reg., 2009. - Vol. 17. - P. 1-18.
Review
For citations:
Alexeeva N.T., Nikityuk D.S., Glukhov A.A. MORPHOLOGICAL REACTION OF MAST CELLS IN REPARATIVE REGENERATION IN THE SKIN UNDER THE INFLUENCE OF REGIONAL FACTORS. Morphological newsletter. 2014;22(3):20-30. (In Russ.) https://doi.org/10.20340/mv-mn.2014.0(3):20-30
Views:
227
