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STRATEGIES FOR IMPROVING TREATMENT OUTCOMES IN CHRONIC PARAPROCTITIS

https://doi.org/10.20340/mv-mn.2025.33(4).982

Abstract

In the article is presented the evaluation of the influence of the preliminary stage of draining ligature on the processes of remodeling of connective tissue in chronic paraproctitis. The analysis of patients was conducted, to whom excision of pararectal fistula was performed. All patients were divided into 2 groups: main group (with preliminary ligature drainage of the fistulous tract) and comparison group (without drainage). By the method of trichrome staining by Mason it was established the reliable predominance of mature collagen of type I and ordered structure of stroma in the main group. Clinically this was accompanied by reduction of frequency of recurrences and reduction of terms of healing. In the course of the research it was confirmed that preoperative ligature drainage in chronic paraproctitis is a clinically effective method, reliably reducing the frequency of recurrences and improving the indicators of the early postoperative period. The revealed interrelation between favorable morphological changes and improvement of clinical results justifies the application of stepwise ligature treatment in patients with complex forms of chronic paraproctitis.

About the Authors

Anastasiya G. Zhirkova
Razumovsky Saratov State Medical University, Saratov
Россия

Assistant of the Faculty Surgery and Oncology Department


Competing Interests:

The Author declares that he did have no conflicts of interest in planning, implementing, financing and using the results of this study



Sergey V. Kapralov
Razumovsky Saratov State Medical University, Saratov
Россия

Doctor of Medical Sciences, Docent, Head of the Faculty Surgery and Oncology Department


Competing Interests:

The Author declares that he did have no conflicts of interest in planning, implementing, financing and using the results of this study



Artem M. Myl'nikov
Razumovsky Saratov State Medical University, Saratov
Россия

Assistant of the Pathology Department


Competing Interests:

The Author declares that he did have no conflicts of interest in planning, implementing, financing and using the results of this study



Grigorii A. Klimenko
Razumovsky Saratov State Medical University, Saratov
Россия

Assistant of the Faculty Surgery and Oncology Department


Competing Interests:

The Author declares that he did have no conflicts of interest in planning, implementing, financing and using the results of this study



Maksim А. Polidanov
REAVIZ Private University, Saint-Petersburg
Россия

Specialist of the Scientific Research Department


Competing Interests:

The Author declares that he did have no conflicts of interest in planning, implementing, financing and using the results of this study



Kirill A. Volkov
Razumovsky Saratov State Medical University, Saratov
Россия

Student


Competing Interests:

The Author declares that he did have no conflicts of interest in planning, implementing, financing and using the results of this study



References

1. Salgado-Nesme N et al. LIFT procedure: postoperative outcomes, risk factors for fistula recurrence and continence impairment. Updates Surg. 2024;76(3):989-997. https://doi.org/10.1007/s13304-024-01818-2

2. Litta F, et al. Simple fistula-in-ano: is it all simple? A systematic review. Tech Coloproctol. 2021;25(4):385-399. https://doi.org/10.1007/s10151-020-02385-5

3. Almughamsi AM, Elhassan YH. Understanding the anatomical basis of anorectal fistulas and their surgical management: exploring different types for enhanced precision and safety. Surg Today. 2025;55(4):457-474. https://doi.org/10.1007/s00595-025-02995-2

4. Vasil'ev SV, Gor IV, Nedozimovanyi AI i dr. Dreniruyushchaya ligatura v lechenii paraproktita. Ambulatornaya khirurgiya. 2021; 2: 89-95. In Russian

5. Kiernan JA. Histological and Histochemical Methods: Theory and Practice. 5th ed. Scion Publishing Ltd. 2015; - S. 571


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For citations:


Zhirkova A.G., Kapralov S.V., Myl'nikov A.M., Klimenko G.A., Polidanov M.А., Volkov K.A. STRATEGIES FOR IMPROVING TREATMENT OUTCOMES IN CHRONIC PARAPROCTITIS. Morphological newsletter. 2025;33(4). (In Russ.) https://doi.org/10.20340/mv-mn.2025.33(4).982

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ISSN 1812-3171 (Print)
ISSN 2686-8741 (Online)