Asthma is the leading allergic disorder. Organs of the digestive system are often involved in this pathological process. There is currently no complex morphological research of the response of the mucous membranes of the gastrointestinal tract to allergic injury and to various methods of treatment of asthma. The aim of this study was to determine the morphological ultra structural features of the duodenal mucosa cells in bronchial asthma of varying severity. As a material for research we used duodenum biopsies of 19 patients with controlled mild asthma, 15 patients with asthma of moderate severity and 12 patients with severe asthma. Semi thin sections were studied in the light microscope with digital image analyzer. Ultra thin sections were examined by transmission electron microscope. It was established that statistically significant morphological violations in the secretors and epithelial cells of duodenum mucosa were observed for each group at different severity of bronchial asthma. It was revealed that complex basic therapy of bronchial asthma of moderate severity had a stabilizing effect on epithelial cells of duodenum. The possibility of extending the remodeling process on organs of the gastrointestinal tract in bronchial asthma is discussed.

The air of the present was to perform of the cytoarchitectonic feature of cortical areas 44 and 45 of human brain of men aged 19-32 years in comparison with the brains of men aged 55-71 years. All men’s were without any nerves deseases. Series of continuous frontal sections of thickness - 20 mkm, stained with cresyl violet by the Nissl method, were used to study the brains. The results showed that brains of men aged 55-71 years were significantly different from the brain of more young men. The cytoarchitectonic organizations of men aged 55-71 are characterized by age changing. In speech-motor cortex of brains of men aged 55-71 increasing of density of glia, glia-neuron index, are increasing. We found the changing of cytoarchitectonic structure of speech-motor cortex is much more clear in cytoarchitectonic layer V in corpasion wich layer III.

By using methods of immunocytochemistry, transmission electron microscopy, light microscopy we studied the effect of mexidol on synthesis and secretion of atrial natriuretic peptide in cardiac myocytes in rats in early postreperfusion period. We found significant increase in the number of granules contain atrial natriuretic peptide in cardiac myocytes and preserve miocardial ultrastructure. These materials informed about positive effect of mexidol on atrial natriuretic peptide accumulation and release due to cytoprotective properties of the drug in early postreperfusion period.

The functional morphology of the lower uterine myocytes in rats during pregnancy and delivery was studied by light, phase-contrast, and electron microscopy. In the myometrium the dynamic changes were observed in the cells structure of two differon layers: myocytes and fibroblasts. Functionally significant subpopulations include the large leiomyocytes in supravascular layer of myometrium and small leiomyocytes in submucosal layer. Pregnancy and delivery contribute to phenotypic transformation of myocytes changing their function from contractile to synthetic with the following active extracellular matrix synthesis. Particular functional importance belongs to differon of fibroblasts carrying out two priority functions: secretory and pacemaker.

36 mature young female Wistar rats conducted an experimental study of the effect of pharmacological blockade kisspeptine receptors on rat’s estrous cycle. Found that kisspeptin has a regulating effect on the estrous cycle of rats. The block of kisspeptine receptors leads to a prolonged disruption of the estrous cycle, consisting in the ovulation phase disappearance and the development of secondary infertility.

The apoptotic morphological changes of bovine granulosa cells from intact and atretic follicles were elucidated. The five morphological types of granulosa cells including cells in necrosis were elaborated using unique fluorescent dyes. It has been established that the frequency of granulosa cells in the late stages of apoptosis in the bovine follicles on the stage of atresia is significantly prevailed. The frequency of granulosa cells on the stage of necrosis in rare atretic follicles does not exceed the percentage of 8. It was concluded that the fluorescent technique to detect apoptosis is a very valuable tool to get understanding about fate of oocytes in the follicles on the stage of atresia.

Experimentally investigated changes in bone matrix upon removal of its organic or mineral components. Were measured mass, the total volume and the true density of compact bone samples before and after decalcification, before and after annealing at 500 and 900С. In each of the compared states by centrifugal porosimetry method was determined porosity structure of the samples . It is shown that after the removal of any components of the bone (mineral or organic ) matrix retains its porosity structure consisting of a central channel osteons, lacunae and connecting tubules.

To solve this goal accomplished comparative histological , electron microscopic and morphometric study of the structural components of the basal decidua without pathology and premature detachment. In the course of scientific research used organometriya, sightseeing and elective procedure, a stain on the laser, the basic structures of shell morphometry, electron microscopy decidual cells and cell-cell contacts. The obtained results of morphological comparisons and statistical analysis allowed to establish predisposing, triggering factors, and suggest a mechanism of abruptio placentae. To confirm the pathogenesis of retinal detachment planned IHC - e study a number of factors.

Experimentally established that during the first day after acute blood loss occurs expressed morphological changes in the adrenal glands in the cortex and medulla, indicating a highfunctional stress of the organ.

Studied 24 mucosal biopsy 12 tiperstnoj, skinny - the ligament Treytsa and 30 cm distal to it, ileum 6 patients with epithelial coccygeal cyst of the colon and small intestine intact endoscopically . Evaluation by these sections of the small intestine was performed on 36 morphometric parameters . Mucosa by 12 tiperstnoj intestines is known to differ morphologically from other  mucosal departments of the small intestine by the presence in it of submucosal glands, mucous membrane in the jejunum and distal to the ligament Treytsa its 30 cm differ by 8.3% morphometric parameters taken into account ; morphometric study of mucosal jejunum and ileum revealed differences by 38.9% and 50.0 % parameters that should be considered when assessing the inflammatory changes that have evolved in these pathological processes.

The article provides information about the anatomy and topography of extraorgan lymph vessels of the uterus, rectum, bladder and how they appear in people of different ages and sex.